GENERAL INFORMATION ABOUT THE STUDY
The study hopes to determine the level of acceptability of COVID-19 vaccines for mass vaccination and the willingness of the Ghanaian population to participate in a clinical trial for a future COVID-19 candidate vaccine.
The COVID-19 disease, which is caused by SARS-CoV-2, is spread through infectious droplets and aerosols from an infected person through the mouth, nose and eyes and by indirect contact with surfaces contaminated with infectious droplets.
The development of vaccines may help reduce transmission, morbidity, and mortality caused by the virus by providing protection to the susceptible or vulnerable population. Any vaccine candidate produced must be taken through clinical trials to ensure that it is safe and offers adequate protection. A clinical trial typically goes through four (4) phases;
PHASE I:
Usually test the vaccine candidate for the first time in a small group of people to evaluate a safe dosage range and identify side effects.
PHASE II:
Test vaccines that have been found to be safe in phase I but now in a larger group of human subjects to monitor for any adverse effects.
PHASE III:
Conduct trials for larger populations and in different regions and countries. This phase is especially important as it takes into consideration biological variations among the human population.
PHASE IV:
Takes place after country approval to identify rare side effects and other unanticipated effects at the population level.
A few vaccines have already been authorized for emergency use.
This study seeks to assess issues of acceptance and awareness around vaccine development in general, and COVID-19 specifically, amongst the Ghanaian population. This may help provide information for future vaccine development and community entry for mass vaccination.